Combined preparation as-dihydroergocriptine – dehydrated derivative of ergot, blocks a1 and a2 adrenergic receptors. Provides dopaminergic, serotonergic action reduces erythrocyte and platelet aggregation, vascular permeability decreases, increasing the number of functioning capillaries, improves blood circulation and metabolism processes in the brain, brain tissues increases resistance to hypoxia.
Caffeine has psychoactive and analeptic action, strengthens the processes of excitation in the cerebral cortex increases mental and physical performance, reduce fatigue and sleepiness, increases the reflex excitability of the spinal cord, stimulates the respiratory and vasomotor centers, has a diuretic effect.
When peroralyyum reception dihydroergocriptine absorption is accelerated in the presence of caffeine (time to maximum concentration of 0.5 hours).
The maximum concentration after oral administration of 8 mg of a-dihydroergocriptine 227 pg / ml and the half life time – less than 2 hours.
Indications for use.
• reduction of mental alertness, impaired attention and memory, disorientation in space caused by age-related changes;
• cerebrovascular insufficiency (including as a result of cerebral atherosclerosis);
• the effects of cerebral circulation;
• migraine prophylaxis;
• vestibular and labyrinth disorders (dizziness , tinnitus, Gipoakuzija) of ischemic origin;
• Meniere’s disease;
• retinopathy (diabetic and hypertensive);
• peripheral arterial circulatory disorders (Raynaud’s disease and syndrome);
• venous insufficiency.
Individual hypersensitivity to the drug.
Pregnancy and lactation,
No clinical data on the use of trenbolone acetate kits during pregnancy and lactation. Use of the drug during breastfeeding may reduce lactation.
Dosage and administration.
Inside (during meals, with a small amount of liquid) to 1 \ 2 tablet 2-1 times a day. The duration of treatment 2-3 months, 1-2 times a year can be carried out if necessary treatments.
On the part of the gastrointestinal tract: nausea, gastralgia, dyspepsia, when these manifestations removal of the drug is needed. Rarely (less than 1% of cases) – dizziness, agitation, headache. Very rarely (less than 0.1% of cases), allergic reactions, tachycardia, hypotension.
Symptoms – increased severity of side effects. Treatment is symptomatic.
Interaction with other drugs.
When concomitant administration trenbolone acetate kits and antihypertensive drugs may develop hypotension. Caffeine reduces the effect of hypnotics.
trenbolone acetate kits has a vasodilatory effect, without affecting systemic blood pressure. Appointment trenbolone acetate kits hypertensive patients does not exclude the need for the use of antihypertensive drugs. Contained in the preparation of caffeine can cause sleep disturbance, tachycardia.